NMR and MS Infrastructure

NMR-instruments

The Department of Molecular Sciences has two NMR spectrometers, both installed in 2012:

1. A Bruker Avance III 600 MHz equipped with a 5-mm ¹H/¹³C/¹⁵N/³¹P Cryoprobe and with a cooled SampleJet sample changer for 5x96 samples and 30 spinner positions.
2. A Bruker Avance III 600 MHz equipped with a 4-mm ¹H/¹³C high-resolution magic angle spinning (HR-MAS) probe, a 4 mm (1H-19F)/(15N-31P) CPMAS probe and a 5-mm BB/¹⁹F-¹H Smartprobe and a sample changer accommodating 120 spinners

The instruments, are used for example in metabolomics research, for structural analysis of biomolecules such as polysaccharides, proteins,  and secondary metabolites. Metabolomics studies involve analysis of biofluids or extracts by high-resolution solution state NMR as well as analysis of intact tissues by HR-MAS NMR.

MS-instruments

The department of Molecular Sciences has four mass spectrometers,

1. A Bruker MaXis Impact ESI-QTOFMS (2011)
2. A Bruker AmaZon speed ETD ESI-ITMS (2011)
3. A Bruker MALDI-TOF/TOF (2014)
4. A UHPL Q-exactive Orbitrap (from 2020)

The instruments are used for research in the field of organic chemistry natural products chemistry and metabolomics.