Metabolomics

The concentration and pattern of metabolites (metabotype) are determined using high-throughput analytical methods i.e., nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS). The department of Molecular Sciences is equipped with modern, high-end instruments for NMR and MS-based metabolomics.

The metabolomics based research at the department of Molecular Sciences is performed in close collaboration with researchers from other field to generate a multidisciplinary research platform. The metabolomics based research includes both method development and application.

Example projects in metabolomics:

• Development and validation of novel NMR and MS methods for measuring the profile of metabolites.
• Identification and validation of diagnostic and prognostic biomarker of chronic disease i.e. prostate cancer, type II diabetes, and Alzheimer disease.
• Establishing strategies for translating metabotype into point-of-care clinical practice (personalized medicine).
• Identification of metabolic responses of signaling pathway involved in development and progression of chronic diseases.
• Identification of health promoting characteristics of food products.
• Monitoring the toxicity of environmental pollutants in aquaculture.
• Optimization of nutritional properties of feed in aquaculture.
• Developing strategies for the application of metabolomics as a new generation of selection tools for crop improvement.
• Developing strategies to link metabolomics with quality traits in crop plants.