Analytical Natural Products Chemistry
The following natural products will be covered: Carbohydrates, lipids, nucleic acids, amino acids, peptides, terpenes, steroids and alkaloids.
The following analytical techniques will be covered: Spectroscopy (NMR, MS, IR, UV), chromatography (GC, HPLC, TLC).
Course evaluation
Additional course evaluations for KE0076
Academic year 2023/2024
Analytical Natural Products Chemistry (KE0076-40145)
2024-03-20 - 2024-04-25
Academic year 2022/2023
Analytical Natural Products Chemistry (KE0076-40154)
2023-03-22 - 2023-04-27
Syllabus and other information
Syllabus
KE0076 Analytical Natural Products Chemistry, 7.5 Credits
Analytisk naturproduktkemiSubjects
Food Science Chemistry Chemistry Food scienceEducation cycle
Bachelor’s levelModules
Title | Credits | Code |
---|---|---|
Single module | 7.5 | 0001 |
Advanced study in the main field
First cycle, has less than 60 credits in first-cycle course/s as entry requirementsBachelor’s level (G1F)
Grading scale
The grade requirements within the course grading system are set out in specific criteria. These criteria must be available by the course start at the latest.
Language
EnglishPrior knowledge
15 credits basic knowledge and skills in general, organic and biochemistry. At least 5 credits of the 15 must be in organic chemistry.Exemption from entry requirements in Swedish.
Objectives
After completed course, the student will be able to:
describe the names, structures, characteristic properties, occurrence, biosynthesis, as well as suitable methods for the analysis, for the majority of the most important groups of natural products as well as for chemical structures found in food.
describe the principles for some of the more common methods for chemical analysis and separation.
execute and interpret data from experiments based some of the more common methods for chemical analysis and separation.
analyse, report and present chemical results both in written and in oral form.
Content
Lectures, seminars, exercise sessions and laboratory work are used during the course. Course introduction, laboratory introduction, laboratory work, execution of project work as well as presentation of the project are compulsory activities.
Properties, such as names, structures and reactivities, occurrence and biosynthesis, of the following groups of natural products and chemical structures often found in food stuffs will be covered in the course:
carbohydrates
amino acids
peptides/proteines
nucleic acids
fatty acids
polyketides
terpenes
steroides
phenylpropanoides
alkaloides
In addition, the following techniques for isolation and analysis of natural products will be covered:
extraction methods
chromatography (GC, HPLC, TLC, etc.)
spectroscopy (NMR, MS, UV/VIS, IR, etc.)
Each student will participate in a small project in which a compound found in e.g. Nature or in food stuffs will be isolated, purified, characterised and/or quantified.
Grading form
The grade requirements within the course grading system are set out in specific criteria. These criteria must be available by the course start at the latest.Formats and requirements for examination
Passed written final exam, passed oral and written reports of the project, passed compulsory laboratory reports and active participation in other compulsory activities
If a student has failed an examination, the examiner has the right to issue supplementary assignments. This applies if it is possible and there are grounds to do so.
The examiner can provide an adapted assessment to students entitled to study support for students with disabilities following a decision by the university. Examiners may also issue an adapted examination or provide an alternative way for the students to take the exam.
If this syllabus is withdrawn, SLU may introduce transitional provisions for examining students admitted based on this syllabus and who have not yet passed the course.
For the assessment of an independent project (degree project), the examiner may also allow a student to add supplemental information after the deadline for submission. Read more in the Education Planning and Administration Handbook.
Other information
The right to participate in teaching and/or supervision only applies for the course instance the student was admitted to and registered on.
If there are special reasons, students are entitled to participate in components with compulsory attendance when the course is given again. Read more in the Education Planning and Administration Handbook.
Additional information
The prerequisites can be fulfilled by having followed the courses KE0062, KE0063 and KE0064 and:i. having passed course modules corresponding to at least 15 credits within the courses mentioned above
and
ii. having passed course modules corresponding to at least 5 credits in organic chemistry
The course is given in Swedish if only Swedishspeaking teachers and students participate.
Responsible department
Department of Molecular Sciences
Further information
Litterature list
1) Natural products: The Secondary Metabolites
**Author: **James R. Hansson
**ISBN: **0-85404-490-6.
Suggested reading: -Analytical chemistry: p. 28-30 -Lipids and polyketides: p. 105-111 -Terpenes: p. 6-14, 112-119 -Phenylpropanoids: p. 15-17, 119-121 -Alkaloids: p. 18-21, 121-124
2) Chemistry (3rd ed)
Authors: Blackman, Bottle, Schmid, Mocerino and Wille
**ISBN: **9780730311058 (paperback)
Suggested reading: -Analytical chemistry: p. 874-940. -Carbohydrates: p. 955-958, 984-1008 -Peptides: p. 1060-1090 -Lipids and polyketides: p. 1043-1047 -Terpenes: p. 942, p. 961 -Alkaloids: p. 848.
3) Chemistry. Human Activity, Chemical Reactivity
**Authors: **P. Mahaffy, R. Tasker, B. Bucat, J.C. Kotz, G.C. Weaver, P.M. Treichel, J.E. McMurry
**ISBN: **9780176684082
Suggested reading: -Analytical chemistry: p. 18, 67-81, 73-74, 306-317, 323, 345, 446, 785-787, 832-839, 878-880, 913-919, 990-993, 1046-1048 -Carbohydrates: Chapter: 29.1 & 29.2, & p. 961-962 -Peptides: Chapter 29.1 & 29.3 -Lipids and polyketides: Chapter 24.12 -Alkaloids: Chapter 25.
4) Compendium - Lectures
Comment: Provided electronically via Canvas.
5) Compendium - Laboratory exercises
Comment: Provided electronically via Canvas.
6) Compendium - Exercises and solutions
Comment: Provided electronically via Canvas.