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PVS0141

Introduction to bioinformatics

The course aims to give the student a solid foundation in the basic methods of bioinformatics. It will cover the theories, algorithms and practical applications of computer-based methods for analysis of DNA sequences and protein structures. The topics to be covered include:

- biological databases

- homology analysis

- sequence analysis (with emphasis on the package EMBOSS and UGENE)

- statistics and R introduction

- web-based tools for analysis

- the Unix operating system

- phylogeny

- comparative genomics

- functional genomics

- Next Generation Sequencing (NGS)



The course is mainly based on lectures, interactive computer exercises and web-based tutorials.

Syllabus and other information


Syllabus

PVS0141 Introduction to bioinformatics, 10.0 Credits

Subjects

Bioinformatics

Education cycle

Postgraduate level

Grading scale

Pass / Failed

Prior knowledge

Admitted to a postgraduate program in animal science, biology, veterinary medicine, food science, nutrition, nursing, bioinformatics or similar subjects, or to a residency program in veterinary science. Some knowledge in biology or cell biology/molecular genetics.

Objectives

After completion of the course, the student should be able to: - understand and describe the basic principles of bioinformatics - independently carry out comparisons of protein and DNA sequences, and to interpret the results - work within Unix/Linux operating systems - build a bioinformatics "workbench" with publicly-available programs that are suited to his/her own needs - use biological databases - describe the statistical methods on which bioinformatics is based - perform bioinformatics analysis and critically evaluate, validate and judge the results

Content

The course aims to give the student a solid foundation in the basic methods of bioinformatics. It will cover the theories, algorithms and practical applications of computer-based methods for analysis of DNA sequences and protein structures. The topics to be covered include: - biological databases - homology analysis - sequence analysis (with emphasis on the package EMBOSS and UGENE) - statistics and R introduction - web-based tools for analysis - the Unix operating system - phylogeny - comparative genomics - functional genomics - Next Generation Sequencing (NGS) The course is mainly based on lectures, interactive computer exercises and web-based tutorials.

Additional information

The participants must bring own computers. The course will take place in the SLU campus Ultuna in Uppsala. Course application: by e-mail to course coordinator. The course is given jointly with the advanced course SLU-30254 Bioinformatics 15.0 HEC, and is part of the GS-VMAS Research School at SLU.



For application: https://www.slu.se/gs-vmas-courses

Responsible department

Department of Animal Breeding and Genetics