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Laura Okmane

Laura Okmane
My research interests lie in protein science. I use methods such as X-ray crystallography, NMR spectroscopy, and various biochemical assays to study carbohydrate-active enzymes, their molecular function and structure.

Teaching

2020 - 2022
Teacher in laboratory courses
Fundamentals in Chemistry II: Biochemistry
Swedish University of Agricultural Sciences, Department of Molecular Biology, Uppsala, Sweden

2016-2018 
Teacher's assistant in multiple microbiology laboratory courses
University of Latvia, Faculty of Biology, Riga, Latvia

Research

2023 - present

NMR studies of protein-glycan interactions using uniformly 13C -labelled glycans

2018 - 2023
Structure and function of expansins and homologous enzymes

Background

2023
Doctor of Philosophy in Biology, specialisation in biotechnology
Swedish University of Agricultural Sciences, Uppsala, Sweden

2017
Master of Natural Sciences in Biology, emphasis on microbiology and biotechnology
University of Latvia, Riga, Latvia

Supervision

2021
Louise Fitkin
Master’s thesis “Purification, activity assays and crystallization of GtCel45A - a small cellulase enzyme from the brown-rot fungus Gloeophyllum trabeum expressed in Aspergillus nidulans

Selected publications

Laura Okmane; Gustav Nestor; Emma Jakobsson; Bingze Xu; Kiyohiko Igarashi; Mats Sandgren; Gerard Jacob Kleywegt; Jerry Ståhlberg. Glucomannan and beta-glucan degradation by Mytilus edulis Cel45A: crystal structure and activity comparison with GH45 subfamily A, B and C. Carbohydrate Polymers, Volume 277, 2022, 118771, ISSN 0144-8617, https://doi.org/10.1016/j.carbpol.2021.118771

Okmane, L., Fitkin, L., Sandgren, M. and Ståhlberg, J. (2024), The first crystal structure of a family 45 glycoside hydrolase from a brown-rot fungus, Gloeophyllum trabeum GtCel45A. FEBS Open Bio. https://doi.org/10.1002/2211-5463.13774

Okmane, L., Sandgren, M., Ståhlberg, J. et al. 1H, 13C and 15N backbone resonance assignment of Cel45A from Phanerochaete chrysosporium. Biomol NMR Assign (2024). https://doi.org/10.1007/s12104-024-10182-6

 

Links

https://orcid.org/0000-0001-8260-6230

 


Contact

Postdoctor at the Department of Molecular Sciences; Strukturbiologi
Postal address:
Institutionen för molekylära vetenskaper